Could Tramadol cause diarrhea instead of constipation? I’ve been taking 50mg a day for the past 2 weeks for pain from a failed root canal and I’ve had an upset stomach with loose stools for the past 4 days. I’ve been off of the Tramadol for about 24 hours with no improvements.

I’m concerned that my current diarrhea may be due to C Diff, as I had taken antibiotics (Cefdinir) two weeks ago and the diarrhea began four days ago. I have been taking Pepto-Bismol, but it hasn’t been helping. I’m also wondering if the Tramadol I’m taking could be the cause.

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